Dr Joséphine Groslambert
Subject: Medicine and Biomedical Science, Molecular and Cellular Biochemistry
Department: Calleva Research Centre
Academic position: Calleva Centre Postdoctoral Researcher
Contact
Background
I am a Postdoctoral Researcher in the Thurston Group at the Sir William Dunn School of Pathology and affiliated with Magdalen College’s Calleva Research Centre. I obtained a BSc (Hons) in Molecular Biology at the University of St Andrews, before completing my DPhil at the University of Oxford, under the supervision of Professor Ivan Ahel. During my DPhil, I studied the function and regulation of a post-translation modification of proteins called ADP-ribosylation. Specifically, I studied how the timely reversal of ADP-ribosylation helps protect cells against genomic instability.
For my postdoctoral research in the Thurston group, I will investigate the host immune responses that restrict Burkholderia pseudomallei, the gram-negative bacterium responsible for the tropical disease melioidosis, a disease with a high fatality rate. My work will combine bioinformatics, mammalian genetics, and cell and molecular biology to uncover how host cells sense and defend against this pathogen, with the aim of identifying mechanisms that could inform new approaches to treating or preventing infection.
Department Staff
Professor Richard Cornall
Professor Michael Goldacre
Professor Sir Peter Ratcliffe
Dr Rebecca Shakir
Professor Chris Garland
Professor Peter Sullivan
Professor Sir Adrian Hill KBE
Professor Quentin Sattentau
Professor Maheshi Ramasamy
Dr Dominic Alonzi
Professor Stephen Goodwin
Professor Gero Miesenböck
The Revd Professor Robert Gilbert
Dr Lauren Phillips
Dr Ishbel Henderson
Professor Teresa Thurston