Dr Haram Park

Background

Dr. Haram Park is a neuroscientist whose research focuses on how innate behaviour is expressed and how it is changed within the context of neuropsychiatric diseases. He received his PhD at the Korea Advanced Institute of Science and Technology (KAIST), where he studied how autism spectrum disorder (ASD)-related behaviours are manifested in different genetic models, as well as how disruption of molecular interactions across the synapse leads to disruptions in innate behaviours. Haram joined Prof. Gero Miesenböck’s lab in Oxford as a Postdoctoral Researcher in October 2019 and Magdalen College in March 2020 as a Fellow by Examination. He has held an EMBO Postdoctoral Fellowship since July 2020.

Research

Haram’s current research focuses on recent breakthroughs in the Miesenböck lab that revealed how the ‘need to sleep’ is tracked in the brain. His aim is to take the findings further to understand the details of sleep homeostasis in the brain.

Selected Publications

• Park, Haram, Choi, Y., Jung, H., Kim, S., Lee, S., Han, H., Kweon, H., Kang, S., Sim, W.S., Koopmans, F., Yang, E., Kim, H., Smit, A.B., Bae, Y., Kim, E., 2020. Splice-dependent trans-synaptic PTPδ–IL1RAPL1 interaction regulates synapse formation and NREM sleep. EMBO Journal, 39(11), p.e104150.
• Choi, Y., Park, Haram, Jung, H., Kweon, H., Kim, S., Lee, S., Han, H., Cho, Y.S., Kim, S., Sim, W.S. and Kim, J., 2019. NGL-1/LRRC4C deletion moderately suppresses hippocampal excitatory synapse development and function in an input-independent manner. Frontiers in Molecular Neuroscience, 12, p.119.
• Choi, Y., Park, Haram, Jung, H., Kweon, H., Kang, S., Kim, S., Lee, S.Y., Han, H., Cho, Y., Kim, S., Choi, Y., Sim, W.S., Kim, J., Bae Y., Kim, E., 2019, NGL-1/LRRC4C deletion moderately suppresses hippocampal excitatory synapse development and function in an input-independent manner. Frontiers in Molecular Neuroscience, 12, p119
• Jung, H., Park, Haram, Choi, Y., Kang, H., Lee, E., Kweon, H., Roh, J.D., Ellegood, J., Choi, W., Kang, J., Kim, E., 2018. Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nature Neuroscience, 21(9), p.1218.
• Lee, S., Chung, W., Park, Haram*, Park, H., Yoon, S., Park, S., Park, J., Heo, J., Hu, X., Yoon, S., Kim, Y., Ko, Y., 2017. Single and multiple sevoflurane exposures during pregnancy do not affect offspring behavior in mice. Pediatric Anesthesia. 27(7), pp. 742-751.
• Chung, W., Choi, S.Y., Lee, E., Park, Haram, Kang, J., Park, H., Choi, Y., Lee, D., Park, S.G., Kim, R. … Kim, E., 2015. Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression. Nature Neuroscience, 18(3), pp.435-443.
  *Equal contribution