Gijs van Boxel studied medicine at Magdalen College, Oxford and completed a PhD in bioenergetics and structural biology at the University of Birmingham. He is currently a Specialty Registrar in General Surgery with an interest in Upper Gastrointestinal Surgery.
The Sherrington Lecturer has organisational responsibility for the Clinical Students studying medicine at Magdalen. Gijs has an interest in adult education having completed a Diploma in Learning and Teaching in Higher Education at the University of Oxford.
Gijs’ PhD focused on mitochondrial function, which was followed by a post-doctoral fellowship at the Wellcome Trust Centre for Human Genetics focusing on structure/function of T-cell receptors. More recently, Gijs has developed a research interest in Service Development, Health Economics and Surgical Innovation
Towards an evidence-based management of right iliac fossa pain in the over 50-year-old patient. Gammeri E, Catton A, van Duren BH, Appleton SG, van Boxel GI. Ann R Coll Surg Engl. 2016 Sep;98(7):496-9.
A novel safety mechanism to reduce the risk of inadvertent electrosurgical injury.
van Duren BH, van Boxel GI, Hart A, Newton N. J Med Eng Technol. 2016 Jul;40(5):239-44.
Patients’ and health-care professionals’ awareness of cost: a multicentre survey.
van Boxel GI, van Duren BH, van Boxel EJ, Gilbert R, Gilbert P, Appleton S.
Br J Hosp Med (Lond). 2016 Jan;77(1):42-5.
Elective day-case laparoscopic cholecystectomy: a formal assessment of the need for outpatient follow-up.van Boxel GI, Hart M, Kiszely A, Appleton S. Ann R Coll Surg Engl. 2013 Nov;95(8):e142-6.
The acute abdomen. van Duren BH, Moghul M, Appleton SG, van Boxel GI. BMJ. 2013 Apr 24;346:f2549.
An alternative conformation of the T-cell receptor alpha constant region. van Boxel GI, Holmes S, Fugger L, Jones EY. J Mol Biol. 2010 Jul 23;400(4):828-37.
Myocardial and cerebral infarction due to massive air embolism following endoscopic retrograde cholangiopancreatography (ERCP). van Boxel GI, Hommers CE, Dash I, Goodman AJ, Green J, Orme RM. Endoscopy. 2010;42 Suppl 2:E80-1.
Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors. van Boxel GI, Stewart-Jones G, Holmes S, Sainsbury S, Shepherd D, Gillespie GM, Harlos K, Stuart DI, Owens R, Jones EY. J Immunol Methods. 2009 Oct 31;350(1-2):14-21.
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS, Kranc K, Sainsbury S, Harlos K, Mellins ED, Palace J, Esiri MM, van der Merwe PA, Jones EY, Fugger L. Immunity. 2009 Mar 20;30(3):348-57.
Structure and functional analysis of the IGF-II/IGF2R interaction. Brown J, Delaine C, Zaccheo OJ, Siebold C, Gilbert RJ, van Boxel G, Denley A, Wallace JC, Hassan AB, Forbes BE, Jones EY. EMBO J. 2008 Jan 9;27(1):265-76.
Substitution of tyrosine 146 in the dI component of proton-translocating transhydrogenase leads to reversible dissociation of the active dimer into inactive monomers. Obiozo UM, Brondijk TH, White AJ, van Boxel G, Dafforn TR, White SA, Jackson JB. J Biol Chem. 2007 Dec 14;282(50):36434-43.
The role of invariant amino acid residues at the hydride transfer site of proton-translocating transhydrogenase. Brondijk TH, van Boxel GI, Mather OC, Quirk PG, White SA, Jackson JB. J Biol Chem. 2006 May 12;281(19):13345-54.
Nucleotide binding affinities of the intact proton-translocating transhydrogenase from Escherichia coli. Bizouarn T, van Boxel GI, Bhakta T, Jackson JB. Biochim Biophys Acta. 2005 Jul 15;1708(3):404-10.
Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase. Mather OC, Singh A, van Boxel GI, White SA, Jackson JB. Biochemistry. 2004 Aug 31;43(34):10952-64.
Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core. Broos J, Gabellieri E, van Boxel GI, Jackson JB, Strambini GB. J Biol Chem. 2003 Nov 28;278(48):47578-84.
Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer. van Boxel GI, Quirk PG, Cotton NP, White SA, Jackson JB. Biochemistry. 2003 Feb 11;42(5):1217-26.